Ciprofloxacin, a fluoroquinolone antibiotic, effectively targets a broad range of bacteria. Its activity is particularly strong against Gram-negative organisms.
Gram-negative bacteria susceptible to ciprofloxacin include Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Haemophilus influenzae, and Neisseria gonorrhoeae. However, resistance is a growing concern, so always check local antibiograms for accurate susceptibility data.
Ciprofloxacin’s activity against Gram-positive bacteria is generally less potent than against Gram-negatives. It exhibits activity against Staphylococcus aureus (though methicillin-resistant Staphylococcus aureus (MRSA) often shows resistance), Streptococcus pneumoniae (some strains are resistant), and Streptococcus pyogenes. Again, consult local antibiograms for reliable susceptibility information in your region.
| Gram-negative | E. coli, K. pneumoniae, P. aeruginosa, H. influenzae, N. gonorrhoeae | Resistance is increasing; check local antibiograms. |
| Gram-positive | S. aureus (MRSA often resistant), S. pneumoniae (variable resistance), S. pyogenes | Resistance varies greatly; consult local antibiograms. |
Remember, accurate susceptibility testing is paramount before prescribing ciprofloxacin. Antibiograms offer valuable local data guiding appropriate antibiotic selection.
