Avoid Prazosin in animals with known hypersensitivity to the drug. A prior allergic reaction necessitates careful consideration and likely exclusion.
Severe cardiovascular disease, including significant heart failure or recent myocardial infarction, presents a risk and warrants avoidance. Monitor closely for changes in heart rate and rhythm.
Concurrent use with other vasodilators can cause excessive hypotension. Carefully review the animal’s medication list to avoid dangerous drug interactions.
Prazosin should not be used in Pregnant or lactating animals unless the potential benefits outweigh the known risks. Further research is needed to assess these risks fully.
Animals with Severe hepatic or renal impairment may experience increased drug accumulation, raising concerns about toxicity. Adjust dosages carefully or consider alternatives.
Use caution in Geriatric animals, as they may be more sensitive to the drug’s hypotensive effects. Close monitoring is crucial.
Brain tumors or other neurological conditions that increase intracranial pressure represent a potential contraindication due to the risk of increased cerebrospinal fluid pressure.
