How Prednisone Affects the Liver

Prednisone, while effective for various conditions, can impact your liver. It primarily does this by increasing the production of enzymes involved in metabolism. Elevated liver enzymes, such as ALT and AST, are common side effects, often detected through blood tests. These increases usually resolve once you stop taking prednisone. However, prolonged or high-dose use increases the risk of more serious liver issues, including drug-induced liver injury.

Monitoring Liver Health

Regular blood tests are crucial for monitoring liver function while on prednisone. These checks usually involve measuring ALT and AST levels. Your doctor will determine the frequency of these tests based on your dosage and treatment duration. Report any symptoms like jaundice (yellowing of skin or eyes), dark urine, or abdominal pain immediately, as these could signal liver problems.

Reducing Liver Risks

To minimize liver damage, follow your doctor’s prescribed dosage carefully. Avoid alcohol consumption, which adds further stress on your liver. A healthy diet and lifestyle support overall liver health. Your physician might consider alternative medications if prednisone’s liver impact becomes a concern.