Dapoxetine’s effects can be altered by certain medications. Always inform your doctor about all medications you’re taking, including over-the-counter drugs, herbal remedies, and supplements. This includes antidepressants, particularly SSRIs and SNRIs, as concurrent use may increase the risk of serotonin syndrome, a potentially life-threatening condition.
MAO inhibitors are strictly contraindicated with dapoxetine due to a significantly heightened risk of serotonin syndrome. Avoid using dapoxetine within at least 14 days of stopping an MAOI, and vice versa.
Some medications that affect the liver’s ability to process drugs can alter dapoxetine metabolism. This may lead to increased dapoxetine levels and an elevated risk of side effects. Your doctor should assess your liver function before prescribing dapoxetine and monitor you closely during treatment.
Alcohol consumption can exacerbate dapoxetine’s side effects, including dizziness and nausea. Limit or avoid alcohol while using dapoxetine.
Grapefruit juice interacts with many medications, potentially influencing dapoxetine’s metabolism. Avoid grapefruit juice while taking this medication.
This information is not exhaustive. Consult your physician or pharmacist for personalized advice on potential drug interactions specific to your medical history and current medications. They can help you safely manage any potential conflicts.


