Always inform your doctor about all medications, supplements, and herbal remedies you’re taking, including over-the-counter drugs. Sertraline can interact with many substances.
Certain pain relievers, like NSAIDs (ibuprofen, naproxen), may increase the risk of bleeding. Consult your doctor if you’re on these.
Combining sertraline with MAO inhibitors (used for depression) is dangerous and should be avoided. A significant time gap is needed between stopping one and starting the other.
Serotonin syndrome, a potentially serious condition, is a risk when combining sertraline with other serotonergic drugs (e. g., St. John’s Wort, triptans for migraines, some antidepressants). Monitor for symptoms like confusion, restlessness, and rapid heart rate.
Alcohol can intensify the sedative effects of sertraline, increasing drowsiness and impairing judgment. Limit or avoid alcohol consumption.
Grapefruit juice can interfere with sertraline metabolism, leading to higher blood levels and increased side effects. Avoid grapefruit juice while taking this medication.
Warfarin (a blood thinner) interaction with sertraline may necessitate dose adjustments. Close monitoring of your INR (International Normalized Ratio) is vital.
This information is not exhaustive. Your healthcare provider can provide personalized guidance on potential interactions based on your specific medical history and other medications you take.
