Prednisone can interact significantly with many other medications. Always inform your doctor and pharmacist of all medications, supplements, and herbal remedies you are taking, including over-the-counter drugs. This includes prescription drugs, like those for diabetes, heart conditions, or blood pressure. Combining Prednisone with certain medications can increase the risk of side effects or reduce their effectiveness.
Specific Medication Interactions
For example, Prednisone can interact negatively with blood thinners like warfarin, increasing your bleeding risk. It can also interact with nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen, potentially increasing the risk of stomach ulcers or bleeding. Furthermore, Prednisone can affect blood sugar levels, impacting the effectiveness of diabetes medications. Interactions with drugs used to treat osteoporosis and potassium levels are also possible. Always seek professional advice before mixing Prednisone with other medications.
Substances to Avoid
Alcohol consumption should be minimized or avoided altogether while taking Prednisone, as it can increase the risk of stomach irritation and other side effects. Similarly, avoid grapefruit juice, as it can interfere with the metabolism of Prednisone, altering its effectiveness. Discuss any concerns about interactions with your doctor or pharmacist before making changes to your medication or dietary habits.
