Prednisone reduces inflammation in plantar fasciitis by suppressing the body’s immune response. It achieves this primarily through binding to glucocorticoid receptors within cells. This binding action inhibits the production of inflammatory mediators like prostaglandins, leukotrienes, and cytokines. These mediators are key players in the pain and swelling associated with plantar fasciitis.
Specifically, Prednisone reduces the infiltration of inflammatory cells, such as macrophages and lymphocytes, into the plantar fascia. This decrease in inflammatory cell activity leads to decreased tissue breakdown and promotes healing. The resulting reduction in inflammation translates directly to less pain and improved flexibility in the affected area.
Important Note: Prednisone is a powerful anti-inflammatory medication, and its use should be carefully considered and monitored by a healthcare professional. Long-term use can carry potential side effects. Always discuss treatment options with your doctor before starting any medication.
Remember to follow your doctor’s instructions carefully regarding dosage and duration of treatment. They will tailor the Prednisone regimen to your specific condition and overall health.