Levitra, or vardenafil, works by increasing blood flow to the penis. This happens through the inhibition of a specific enzyme, phosphodiesterase-5 (PDE5).
Here’s how it works step-by-step:
Sexual stimulation triggers the release of nitric oxide (NO). NO activates an enzyme called guanylate cyclase. Guanylate cyclase produces cyclic guanosine monophosphate (cGMP). cGMP relaxes the smooth muscles in the blood vessels of the penis. Relaxed blood vessels allow increased blood flow into the penis, resulting in an erection. PDE5 normally breaks down cGMP, limiting the duration of the erection. Levitra inhibits PDE5, prolonging the effects of cGMP.
Remember, Levitra only works with sexual stimulation. It doesn’t create an erection on its own. Its effectiveness varies based on individual factors such as overall health and the cause of erectile dysfunction.
Potential side effects include headache, flushing, nasal congestion, and indigestion. Always consult your doctor before using Levitra, particularly if you have pre-existing health conditions such as heart disease or high blood pressure.
- Discuss any medications you’re currently taking with your doctor to avoid potential drug interactions. Follow your doctor’s prescribed dosage and instructions carefully. Be aware of potential side effects and seek medical attention if needed.


