Tadalafil works by relaxing the muscles in the prostate and bladder neck. This relaxation reduces pressure on the urethra, the tube that carries urine from the bladder, improving urine flow and reducing symptoms of benign prostatic hyperplasia (BPH).
Specifically, Tadalafil inhibits phosphodiesterase-5 (PDE5). PDE5 breaks down cyclic guanosine monophosphate (cGMP), a molecule that causes smooth muscle relaxation. By blocking PDE5, Tadalafil increases cGMP levels, leading to the muscle relaxation described above.
This mechanism differs from alpha-blockers, another common BPH treatment. Alpha-blockers directly relax the muscles in the prostate and bladder neck, while Tadalafil achieves this indirectly through cGMP modulation. The choice of medication depends on individual patient factors and response.
The 5mg dosage of Tadalafil is often prescribed for BPH because it provides a sustained benefit without the higher risk of side effects associated with higher doses. Remember to consult your doctor to determine the appropriate dosage and treatment plan for your specific needs. They can discuss potential side effects and ensure Tadalafil is the right choice for you.
Important Note: This information is for educational purposes only and does not constitute medical advice. Always consult with a healthcare professional before starting or changing any medication.
