Viagra, or sildenafil, works by inhibiting phosphodiesterase-5 (PDE5). This enzyme breaks down cyclic guanosine monophosphate (cGMP), a crucial molecule for achieving and maintaining an erection.
When sexually stimulated, nitric oxide is released, increasing cGMP levels. This leads to relaxation of the smooth muscles in the penis, allowing increased blood flow. By blocking PDE5, Viagra prolongs the effects of cGMP, thus facilitating an erection.
Specific Effects on Blood Vessels
The increased cGMP levels primarily affect the blood vessels in the corpus cavernosum, the spongy tissue within the penis responsible for engorgement. This targeted action explains Viagra’s specific effect on erectile function.
Dosage Considerations and Individual Differences
Individual responses to Viagra vary. Factors like age, overall health, and other medications can influence efficacy. Always follow your doctor’s instructions regarding dosage and potential drug interactions.
| Liver or kidney function | May require dosage adjustment |
| Heart conditions | Requires careful medical supervision |
| Other medications | Potential for interactions; discuss with your physician |
Important Note: Consult Your Doctor
This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional before starting any medication, including Viagra, to determine the appropriate dosage and address potential risks.
