Administer Zofran (ondansetron) IV slowly, at a rate no faster than 1 mg/min. This minimizes the risk of adverse reactions, including hypotension and bradycardia.
For a 4 mg dose, plan for a four-minute infusion. Always dilute the medication in a compatible solution like normal saline before administration. Careful monitoring of the patient’s vital signs during and after infusion is critical. Observe for any signs of dizziness, lightheadedness, or changes in heart rate or blood pressure.
Pre-medication with antihistamines or corticosteroids may be considered in high-risk patients, particularly those with a history of cardiac issues. Consult your institution’s prescribing guidelines for specific protocols and individual patient needs. Always document the dose, administration rate, and any observed side effects thoroughly in the patient’s medical record.
Remember, deviations from standard protocols require physician approval. Patient safety is paramount. Adherence to these guidelines contributes significantly to safe and effective Zofran administration.
