Your doctor will determine the appropriate imipramine dosage based on your individual needs and response to treatment. Typical starting doses are low and gradually increased.
For adults, treatment usually begins with a low dose, such as 10-25mg at bedtime. This helps minimize daytime drowsiness. The dose is then gradually increased, typically by 25-50mg increments every 3-7 days, under close medical supervision, until the desired effect is achieved or side effects become problematic.
- Typical maintenance dose: Ranges from 50-150mg daily, administered in divided doses. Maximum recommended dose: Generally does not exceed 150mg daily.
It’s crucial to follow your doctor’s instructions precisely. Never adjust your dosage without their explicit consent.
Imipramine is usually administered orally, as a tablet or capsule, with or without food. Consistent daily dosing is key for optimal results.
Take the medication at the same time each day to maintain consistent blood levels. If you miss a dose, take it as soon as you remember unless it’s almost time for your next dose. Never double up on doses. Inform your doctor of any side effects you experience.
Regular monitoring by your doctor is necessary to assess your progress, adjust the dosage as needed, and manage potential side effects. This collaborative approach ensures safe and effective treatment.


