Prednisone can increase your basal metabolic rate (BMR). This means your body burns more calories at rest while taking the medication. The magnitude of this increase varies depending on factors such as dosage and individual responses.
Studies show that higher prednisone doses correlate with a more significant elevation in BMR. This is because prednisone is a glucocorticoid that influences various metabolic processes, including carbohydrate metabolism, protein breakdown, and fat mobilization. Increased protein breakdown, in particular, contributes to a higher caloric expenditure at rest.
However, this increase in BMR doesn’t always translate to weight loss. Prednisone’s impact on appetite is a significant confounding factor. Many individuals experience increased hunger while on prednisone, potentially negating the caloric deficit from the elevated BMR. In some cases, fluid retention also contributes to weight gain.
Consequently, monitoring your weight and overall calorie intake alongside your prednisone use is critical. A balanced diet and regular exercise can help to manage any potential weight fluctuations. Consult your doctor or a registered dietitian to create a personalized plan that takes into account both your medication and your individual needs.
It’s important to remember that individual responses to prednisone vary greatly. Some people experience a noticeable change in their metabolism, while others may see little to no effect. Regular monitoring and open communication with your healthcare provider are vital for optimal management.
