Always inform your doctor about all medications you are taking, including over-the-counter drugs, herbal supplements, and recreational drugs, before starting Sildenafil Zenegra. This is crucial for preventing potentially harmful interactions.
Nitrates
Combining Sildenafil Zenegra with nitrates (found in medications for chest pain) can cause a dangerous drop in blood pressure. This combination should be strictly avoided.
Alpha-blockers
- Alpha-blockers, often prescribed for high blood pressure or enlarged prostate, can increase the risk of low blood pressure when taken with Sildenafil Zenegra. Your doctor might adjust your dosage or recommend alternative treatments.
CYP3A4 Inhibitors
Medications that inhibit the CYP3A4 enzyme (e. g., ketoconazole, erythromycin) can increase Sildenafil Zenegra levels in your blood, potentially leading to increased side effects. Your doctor may adjust your Sildenafil Zenegra dose accordingly.
CYP3A4 Inducers
Conversely, medications that induce the CYP3A4 enzyme (e. g., rifampin, St. John’s Wort) can decrease Sildenafil Zenegra levels, potentially reducing its effectiveness. Discuss this with your doctor.
Other Medications
Certain antidepressants Some blood thinners Specific antifungal medications
These are just examples; many other drugs can interact with Sildenafil Zenegra. Always provide a complete medication list to your doctor or pharmacist for a thorough assessment of potential interactions.
Alcohol
Excessive alcohol consumption can worsen Sildenafil Zenegra’s side effects, particularly low blood pressure and dizziness. Moderate alcohol intake is generally acceptable, but you should always consult your physician.
Grapefruit Juice
Grapefruit juice contains compounds that can inhibit the CYP3A4 enzyme. Avoiding grapefruit juice while taking Sildenafil Zenegra is recommended to prevent potential drug interactions.
