Always inform your veterinarian about all medications your dog is taking, including over-the-counter drugs, supplements, and herbal remedies. Diclofenac can interact negatively with several drug classes. For example, concurrent use with non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen increases the risk of gastrointestinal ulcers and kidney problems. Combining diclofenac with anticoagulants (blood thinners) like warfarin can heighten bleeding risk. Similarly, concurrent administration with ACE inhibitors (used for heart conditions) may lead to decreased kidney function.
Specific Drug Interactions to Avoid
Avoid combining diclofenac with aminoglycoside antibiotics (like gentamicin or streptomycin) as this combination can damage the kidneys. Lithium levels can be affected by diclofenac, necessitating careful monitoring if your dog is on lithium therapy. Methotrexate toxicity may be increased with diclofenac, requiring close veterinary observation. Finally, consult your vet before using diclofenac with diuretics as this combination may impact kidney function.
Your veterinarian can help determine if the benefits of using diclofenac outweigh the potential risks given your dog’s specific health profile and medication regimen. Open communication with your vet is paramount to ensure your dog’s safety and well-being.
