Prednisone’s Mechanism of Action: Understanding its Effects

Prednisone mimics the action of cortisol, a steroid hormone your body naturally produces. It binds to receptors inside your cells, influencing gene expression.

This interaction triggers a cascade of effects. Prednisone reduces inflammation by decreasing the production of inflammatory molecules like cytokines. It also weakens the immune system, suppressing the activity of immune cells like lymphocytes.

These effects explain why prednisone treats various inflammatory conditions. However, the immune suppression contributes to side effects like increased susceptibility to infections.

Prednisone’s impact on metabolism is significant. It can increase blood sugar levels, affecting individuals with diabetes. It can also influence bone density, potentially leading to osteoporosis with prolonged use. Fluid retention is another common side effect, stemming from changes in sodium and water balance.

The specific effects and their intensity depend on the dosage and duration of treatment. Always follow your doctor’s instructions carefully and report any unusual symptoms promptly.