Immediately seek medical attention if you suspect a carbamazepine overdose. Symptoms can appear within hours and vary widely, but commonly include nausea, vomiting, dizziness, and drowsiness. Severe cases may present with ataxia, seizures, cardiac arrhythmias, or coma.
Treatment focuses on supportive care and reducing drug absorption. Gastric lavage or activated charcoal may be used to remove unabsorbed medication if administered within a few hours of ingestion. Intravenous fluids help maintain hydration and blood pressure. Seizures are managed with intravenous diazepam or lorazepam.
Continuous cardiac monitoring is crucial due to the risk of arrhythmias. Blood carbamazepine levels are regularly monitored to guide treatment. Hemodialysis is rarely indicated unless there’s severe renal impairment or extremely high serum levels.
Close monitoring is necessary for several days post-overdose, as delayed complications such as hyponatremia or hepatic dysfunction can occur. Regular neurological assessments help detect any developing neurological deficits.
Patient education on safe medication use and the importance of seeking medical attention in case of suspected overdose is paramount to prevent future incidents. This includes proper storage of medications away from children and clear communication with healthcare providers about any changes in medication regimens.
