Tadalafil is the active ingredient in Cialis. It works by relaxing blood vessels in the penis, allowing increased blood flow necessary for an erection. This effect occurs in response to sexual stimulation.
How Tadalafil Differs from Other PDE5 Inhibitors
Unlike some other medications in its class, Tadalafil boasts a longer half-life, meaning its effects can last up to 36 hours. This longer duration distinguishes it from sildenafil (Viagra) and vardenafil (Levitra). The extended duration allows for more spontaneity in sexual activity.
Understanding Tadalafil’s Mechanism of Action
Tadalafil selectively inhibits phosphodiesterase type 5 (PDE5), an enzyme that regulates blood flow. By blocking PDE5, Tadalafil increases the levels of cyclic GMP, a molecule that promotes vasodilation (widening of blood vessels). This results in enhanced blood flow to the penis.
Important Considerations Regarding Tadalafil
Consult your doctor before using Tadalafil, especially if you have heart conditions, high blood pressure, or are taking other medications. Tadalafil can interact with nitrates, leading to dangerously low blood pressure. Always follow prescribed dosages and instructions carefully. Potential side effects, although uncommon, include headaches, flushing, and indigestion.
