Viagra, or sildenafil, primarily works by inhibiting a specific enzyme called phosphodiesterase-5 (PDE5). This enzyme typically breaks down cyclic guanosine monophosphate (cGMP), a crucial molecule for achieving and maintaining an erection.
By blocking PDE5, Viagra allows cGMP levels to rise. Increased cGMP leads to relaxation of smooth muscle in the penis, increasing blood flow and facilitating an erection in response to sexual stimulation. It’s important to remember Viagra does not directly cause an erection; it enhances the body’s natural response to sexual stimulation.
This mechanism is specific to the penis, minimizing side effects in other areas of the body. However, because PDE5 is present in other tissues, side effects such as headaches, flushing, and visual disturbances can occur, though they are usually mild and temporary.
The duration of Viagra’s effect varies, typically lasting several hours. The precise timeframe depends on individual factors like metabolism and dosage.
Before using Viagra, it is crucial to consult a healthcare professional to discuss potential risks and interactions with other medications.
