Viagra’s Mechanism of Action and Intended Use

Viagra, or sildenafil, primarily treats erectile dysfunction (ED) in men. It works by increasing blood flow to the penis.

This happens because Viagra inhibits a specific enzyme, phosphodiesterase-5 (PDE5). PDE5 normally breaks down a substance called cyclic guanosine monophosphate (cGMP), which relaxes smooth muscles in the penis, allowing blood vessels to dilate.

    By blocking PDE5, Viagra elevates cGMP levels. Increased cGMP leads to greater blood vessel relaxation. This enhanced blood flow facilitates an erection in response to sexual stimulation.

It’s crucial to understand Viagra only assists in achieving an erection; sexual stimulation is still required to trigger the process.

Beyond ED, Viagra has also shown efficacy in treating pulmonary arterial hypertension (PAH), a condition marked by high blood pressure in the arteries leading to the lungs. The mechanism remains similar – improved blood flow due to PDE5 inhibition.

For ED: Viagra is typically taken as needed, approximately 30-60 minutes before sexual activity. For PAH: Dosage and frequency depend on individual needs and are determined by a physician.

Always consult a healthcare professional before using Viagra. They can assess your health status, discuss potential side effects (such as headaches, flushing, or nasal congestion), and determine if Viagra is appropriate for you.