Recognizing Signs of Agranulocytosis: The Primary Reason to Hold

Immediately discontinue Clozaril if you observe any signs of infection, such as fever (greater than 100.4°F or 38°C), sore throat, mouth sores, or unusual fatigue. These can be early indicators of agranulocytosis, a potentially life-threatening drop in white blood cells.

Understanding the Severity

Agranulocytosis severely compromises the body’s ability to fight infection. Even a minor infection can become rapidly serious. Look for chills, body aches, and swollen lymph nodes. Don’t hesitate; report any suspicious symptoms to your doctor immediately.

Monitoring Blood Counts: A Crucial Step

Regular blood tests are critical for detecting agranulocytosis before symptoms appear. These tests measure your white blood cell count, specifically neutrophils. A significant decrease necessitates immediate Clozaril cessation.